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ترشح سروتونین می شود. حس تنهایی و افسردگی زمانی پیش می آید که
میزان سروتونین در بدن کاهش می یابد.
به همین منظور بیشتر داروهای ضد افسردگی بر افزایش میزان سروتونین تمرکز دارند.
دوپامین یک ماده شیمیایی عصبی (در مغز پیامرسان عصبی و
در خون نقش هورمون) حیاتی در بدن ماست.
سروتونین ، نوشته میشل هولبک
با این حال، کارشناسان به این نتیجه رسیده اند که آیا سطح سروتونین در افراد
مبتلا به سندرم خستگی مزمن (CFS یا
ME / CFS ) بالا یا پایین است یا خیر.
برخی مطالعات نشان می دهد که مشکل در ME / CFS ممکن است در فعالیت گیرنده
های سروتونین کم باشد، که می تواند به این معنی باشد که مغز
به درستی از سروتونین استفاده
نمی کند، حتی اگر مقدار زیادی در دسترس باشد.
یک مطالعه جدید نشان می دهد واکنش های
خود ایمنی ممکن برای سروتونین. تفاوت اصلی بین ملاتونین و سروتونین در این است که ملاتونین هورمونی است که به
ما کمک می کند بخوابیم در حالی که سروتونین یک انتقال دهنده عصبی است که به ما کمک
می کند تا فرد دیگر از خواب بیدار شویم.
دوپامین از اسید آمینه تیروزین
سنتز می شود، در حالی که سروتونین
از اسید آمینه تریپتوفان ساخته می شود.
افرادی که اختلالات و مشکلات عقلی
و ذهنی دارند، دارای سطح سروتونین پایینی می باشند.
به نظر میرسد درمان با SSRI در مقایسه با دارونما برای PE بهطور قابل توجهی تعدادی از
پیامدهای مهم را از نظر بیمار مانند بهبود نشانهها، رضایت از رابطه جنسی و کنترل قابل درک بر انزال بهبود میبخشد.
اثرات نامطلوب عبارتند از افزایش مختصر در موارد ترک درمان به دلیل بروز عوارض جانبی همچنین
افزایش قابل توجه در نرخ عوارض جانبی.
مشکلات تاثیرگذار بر قطعیت شواهد پیامدها، محدودیتها و عدم دقت بودند.
فیبرومیالژیا یک وضعیت مزمن و با
اتیولوژی ناشناخته است که به صورت
بالینی تعریف میشود و ویژگی آن،
درد مزمن منتشری است که اغلب با اختلالات
خواب، اختلال عملکرد شناختی و خستگی
همراهی دارد.
تاثیر ورزش بر سبک زندگی
بهطور تخمینی ۷۰٪ از مصرفکنندگان عوارضی را در حوزه اختلالات جنسی تجربه میکنند.
اثر این داروها از سوی روانشناسان به صورت «کاهش احساس» بیان شدهاست.
بیماران افسرده میزان کمتری از متابولیتهای
سروتونین در مایع مغزی نخاعی و بافت مغزی دارند.
در اوایل صبح به صورت طبیعی میزان بیشتری دوپامین
در بدن ترشح می شود هر چه می گذرد، میزان دوپامین پایین میآید.
کمبود خواب با مختل کردن این الگو باعث کم شدن میزان دسترسی گیرنده های دوپامین
در مغز میشود که بی حالی، کاهش تمرکز و عدم هماهنگی شناختی را به دنبال
خواهد داشت . اگر در طول روز می خواهید تجربه بهتر و سرزنده تری داشته باشید حتما ۸ ساعت خواب
شبانه را در برنامه خود در نظر بگیرید.
در آزمایشی مشخص شد روند رشد موشهایی
که دچار کمبود سروتونین میشوند، کند شده و مشکلات تنفسی، قلبی و عروقی، اختلال در خواب و افزایش رفتارهای تهاجمی ایجاد میشود.
در آزمایش دیگری موشهای
ماده که به کمبود سروتونین مبتلا شدند، علاوه بر رفتار بسیار
خشن و تهاجمی، بچههای خود و دیگر موشها را نیز میخوردند.
بالا و پایین رفتن غلظت سروتونین روی قسمتی از
مغز افراد که میزان خشم و عصبانیت را کنترل میکند،
تأثیرگذار است. گرسنگی و استرس سبب ایجاد
نوسان و کاهش غلظت هورمون سروتونین مغز شده و
هنگامی که افراد گرسنه میشوند، احتمال بروز عصبانیت و خشونت در آنها
افزایش مییابد. غلظت کم سروتونین سبب برقراری ارتباطات کمتر و ضعیفتر از حد
معمول در بخشهای مرکزی مغز میشود.
پژوهشگران دریافتند وقتی چنین اتفاقی رخ میدهد، برای مغز مشکلتر است که واکنشهای عاطفی نسبت به خشم را کنترل کند.
• با خانواده و دوستانتان وقت بگذرانید؛
لمسکردن، بغلکردن، بوسیدن، داشتن روابط جنسی، ابراز
احساساتکردن، حرفهای دلگرمکننده ، تشویقکردن، محبتکردن و شکرگذاری باعث افزایش
هورمون اکسیتوسین در مغز میشود.
بنابراین سعی کنید از لذتهای طبیعی و بدون هزینه که خداوند در اختیارتان
قرار داده استفاده کنید تا شادی
و نشاط در زندگیتان بیشتر ایجاد
شود. فست فودها، قهوه، الکل، نیکوتین
موجود در سیگار، قندهای رژیمی و محصولات حاوی آن مانند نوشابههای رژیمی سبب کاهش غلظت سروتونین مغز میشوند و باید از مصرف آنها توسط نوجوانان ممانعت کرد.
بنابراین در رژیم غذایی نوجوانان تا آنجا
که ممکن است باید سعی کرد از مواد خوراکی افزایش دهنده
سروتونین در مغز استفاده شود و از طرفی از گرسنه
ماندن آنان جلوگیری شود. زمانی که نوجوانان از فعالیتهای درسی
یا ورزشی به منزل برمیگردند قبل از هر چیز لازم است وضعیت گرسنگی بررسی شود و با غذاهای مناسب تغذیه شوند، سپس از آنها خواسته شود
تکالیف درسی را انجام دهند.
با این کار از کمحوصلگی و احیاناً پرخاشگری و توجه نکردن به نصیحتها جلوگیری میشود.
سمیت سروتونین را در حیوانات توصیف می کند
که با بیش فعالی اتونومیک (اسهال، میدریاز
و تاکی کاردی)، علائم عصبی عضلانی (هیپررفلکسی، میوکلونوس، لرزش،
و سفتی)، و تغییر وضعیت ذهنی مشخص
می شود. سابلمینالها ، پیامها و فرکانسهایی
پنهان هستند که قادرند بر روی ناخودآگاه ذهن فرد اثر گذاشته و
قسمت ناخودآگاه را با هدفی که دنبال میکنند که در اینجا به طور خاص، جذب شادی است، همسو نمایند.
در فایل اختصاصی فرکانسیک پرسشهایی وجود دارد که پاسخ دادن به
آنها، میتواند فرکانس ذهنی و ناخودآگاه شما را برای
کارشناسان ما عیان کند. عوارض جانبی سروتونین از مکمل های مانند 5-HTP
اغلب هستند کمتر سپس با نسخه دارو, هر دو
در شدت و فرکانس. در برخی از بیماران, SSRI ها می تواند بسیار موثر و
به طور معمول در درمان طیف متنوعی
از اختلالات ذهنی و جسمی توصیه.
اثر بخشی آنها توسط چگونه به خوبی
به مواد مخدر کار می کند در کاهش علائم زندگی محدود
یک اختلال اندازه گیری, و همچنین عدم وجود عوارض
جانبی سروتونین. اگر کمبود ویتامین B6
دارید ، می تواند بر تولید سروتونین تأثیر بگذارد.
سروتونین از آمینو اسیدی به
نام تریپتوفان سنتز می شود ، بنابراین اگر سطح رژیم غذایی L-تریپتوفان در رژیم غذایی کم باشد ، ممکن است سروتونین شما پایین باشد.
برخی از غذاها شامل مرغ ، آجیل و محصولات لبنی حاوی ال تریپتوفان هستند.
همچنین مطالعات انجام شده
حاکی از آن است که یک اسید آمینه در برخی
از برگهای چای می تواند بر
سطح سروتونین تأثیر بگذارد. دلیل
اینکه زنبورهای وحشی و عقربهای دثاستاکر در زهر نیش خود سروتنین دارند شاید همین عاملیت دردزایی سروتنین برای افزایش درد نیششان در حیوانات بزرگتر باشد.
این سروتنین موجود، در هنگام شکار در
جانداران کوچکتر به دلیل خاصیت انعقاد خون باعث مرگ
شکار خواهد شد. از سروتونین در درمانِ چاقی نیز استفاده
میشود.[۸] سروتونین در دستگاه گوارش از سلولهای
انتروکرومافین در پاسخ به ورود
غذا آزاد میشود. به استثنای گیرندهٔ 5HT3 که دروازه لیگاندی کانال یونی است، همه گیرندههای 5HT از شاخه گیرندههای «هفت
مارپیچ غشاءگذر» هستند که سیستم پیامرسانی ثانویه درون سلولی را فعال میکند.
سندرم مراقب این بیماری در افرادی
ایجاد می شود که در موقعیت وابستگی نقش مراقب اصلی شخص را بازی می کنند.
آکسونهای نورونهای هستههای رافی از سیستم انتقالات عصبی، تقریباً به همه جای سیستم مرکزی
عصبی میرسند. آکسونهای نرونهای در قسمتهای پایینی هستههای رافی در مخچه و
طناب نخاعی پایان مییابند، در
حالی که آکسونهای هستههای رافی بالاتر در کل مغز پخش میشوند.
از آن رو که سروتنین از شاخصهای انعقاد خون است، افزایش ناگهانی و بسیارش در سطوح محیطی باعث درد میگردد.این
پاسخ به این دلیل است که افزایش سروتونین میتواند
حالت تهوع ایجاد کند و داروهایی که گیرندههای
خاص سروتونین را هدف قرار میدهند
میتوانند برای کاهش تهوع و استفراغ استفاده شوند.
در نظر گرفته شدن انتقال دهنده
عصبی ، ما درک می کنیم که سروتونین تأثیر اصلی خود را بر
روی سیستم عصبی مرکزی خواهد گذاشت.
مطالعات علمی نشان می دهد که رابطه عمیقی بین سطح پایین
سروتونین و اختلالات روانی مانند افسردگی یا استرس وجود دارد.
هورمون پروژسترون هم بهخصوص در سه ماه اول بارداری افزایش مییابد.
پروژسترون در دوران بارداری تا حدی برای جلوگیری از انقباضات زودرس رحم به عضلات آرامش بیشتری میدهد و نهتنها روی عضلات رحم عمل میکند بلکه بر روی روده نیز تأثیر می گذارد و باعث
کند شدن حرکات روده میشود. همچنین افزایش ترشح این هورمون در دوران بارداری، می تواند باعث ایجاد خستگی و اندوه باشد.
زعفران میتواند به عنوان یک داروی گیاهی کمک درمانی در کنار دیگر داروهای ضد افسردگی مورد استفاده قرار بگیرید و مفید باشد.
دردسرهای نداشتن تعادل هورمونی هورمون ها، مواد
شیمایی بسیار مهمی هستند که بر عملکرد بسیاری از اندام های بدن تاثیر دارند و تعادل بین آنها از اهمیت بالایی برخوردار است.
استرس می تونه به شدت روی استروژن تاثیر منفی بذاره و
ترشحش به میزان کافی در بدن می تونه استرس
رو کنترل کنه و روی خلق و خو تاثیر مثبت بذاره.
آخه این هورمون تو دوران بارداری و شیردهی در بدن زنان ترشح میشه
و عشق عجیب مادر به فرزند رو شکل
میده. این هورمون در هیپوتالاموس
تشکیل و بعد به غده هیپوفیز منتقل
میشه و ارتباط مستقیم با روابط خانوادگی،
عشق، دوستی و تعاملات اجتماعی بین آدم ها
داره.
تفاوت سروتونین و دوپامین از این دو ماده شیمیایی اساساً می توان به عنوان مواد شیمیایی خوشبختی یاد کرد.
انجام ورزش های هوازی منظمهم به افرادی که مبتلا به بیماری پارکینسون هستند کمک می کند تا وضعیتی که در آن سطوح پایین دوپامین باعث اختلال در توانایی مغز در کنترل حرکات
بدن می شود، بهبود پیدا کند. L- تیروزین اسید آمینه است و پیش ماده ی طبیعی است L-دوپا; مواد شیمیایی مورد استفاده برای تولید دوپامین
در مغز. در حالی که امن زمانی که
در دوزهای پایین استفاده, استفاده بیش از حد برای
مدت زمان طولانی می تواند عوارض جانبی ایجاد.
در بیماری پارکینسون، با از بین رفتن
سلولهای عصبی در قسمت خاصی از مغز،
از دست رفتن دوپامین در همان ناحیه رخ میدهد.
سفتی عضلات با درد همراه خواهد بود و
میتواند طیف وسیعی از حرکات
را محدود کند. علائم و نشانههای بیماری پارکینسون میتواند از شخصی به
شخص دیگر متفاوت باشد. علائم اولیه
این بیماری ممکن است به شکل خفیف بروز کرده
و اصلا قابل تشخیص نباشند.
یکی از راههای حفظ سطح بالای دوپامین، اجتناب
از استرس است که تقریبا غیر ممکن است.
تحقیقات نشان داده است که، ماساژ درمانی برای مقابله با اثرات استرس، سطح کراتین (هورمون
استرس) را کاهش می دهد.
نقش دوپامین در اختلال شخصیت مرزی
مواد مغذی موجود در برخی غذاهای
خاص به مغز میروند و به تولید دوپامین کمک میکنند.
خوردن مقدار زیادی میوه و سبزیجات، به
ویژه موز، میتواند تولید دوپامین
را افزایش دهد. همچنین مصرف پروتئین،
از جمله گوشت بدون چربی، ماهی، لوبیا و پروتئین گیاهی
و نیز غذاهای سرشار از اسیدهای چرب امگا
۳ مانند ماهی سالمون، شاهماهی، صدف چروک، بذر کتان و گردو نیز توصیه میشود.
عوارض جانبی ، که در اوایل مشاهده می شود ، معمولاً
با ترکیب لوودوپا با سایر داروها برطرف
می شوند. به عنوان مثال ، یک عارضه جانبی مهم لوودوپا در صورت استفاده به تنهایی ، حالت تهوع است که در نتیجه دوپامین بیش
از حد به جای مغز در گردش خون
در بدن وجود دارد. در سطح سوم معمولا
علائم جدید ظاهر نمیشوند اما علائم سطح دوم تشدید شده و
ممکن است در زندگی روزمره شما تداخل ایجاد کنند.
در جراجی تحریک مغز عمیق ، جراحان الکترودهایی
در قسمتهای خاص مغز قرار میدهند.
یک ژنراتور به این این الکرودها متصل خواهد شد که پالسهایی را برای کاهش علائم بیماری پارکینسون ارسال میکند.
استراحت مناسب، ورزش و رژیم غذایی سالم و متعادل از مهمترین تغییراتی هستند که باید در رژیم غذایی خود ایجاد
کنید. گفتار درمانی، کار درمانی و فیزیوتراپی نیز از جمله تراپیهایی
هستند که میتوانند علائم فرد مبتلا به
پارکینسون را بهبود ببخشند.
افراد از طریق مصرف مواد پروتئینی، عدم استفاده از چربی اشباع
شده، پروبیوتیک، خوردن باقلا مخملی، ورزش کردن، خواب کافی،
گوش دادن به موسیقی، نور خورشید و مدیتیشن میتوانند میزان دوپامین
را در بدن خود افزایش دهند. به این دلیل,
شما باید با دکتر قبل از مصرف هر گونه مکمل های جدید برای جلوگیری
از تداخلات خطرناک اگر شما با استفاده از داروهای تجویزی را بررسی کنید.
با این حال, عوارض جانبی به احتمال زیاد به رخ می دهد که ترکیب بوستر
دوپامین متعدد یا داروهایی که توابع دوپامینرژیک را تحت تاثیر قرار در مغز.
برخی از شایع ترین عوارض جانبی دوپامین کم شامل
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آگونیستهای دوپامین داروهایی هستند که میتوانند از نشت مایعات از عروق خونی به بخشهای دیگر بدن، که یک مشکل
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سابقه مشکلات قلبی یا فشار خون، بیماری های کلیوی یا کبدی و
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نسل اول از نوع ارگولین است و امروزه کمتر استفاده می شود زیرا خطرات جدی مربوط به قلب و ریه در ارتباط با استفاده از آنها وجود دارد.
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از سوی دیگر گروهی از سلولها مسئولیت
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